FOLFIRINOX is a chemotherapy regimen that is commonly used to treat pancreatic cancer. It is a combination of four different chemotherapy drugs:

FOL = FOLinic acid (also called leucovorin)

= Fluorouracil (also called 5-FU)

IRIN IRINotecan

OX = OXaliplatin

The FOLFIRINOX regimen is usually given on a two-week cycle. During each 2-week cycle, you will have FOLFIRINOX treatment on day 1 at the hospital. Your nurse will also start an IV of fluorouracil that will continue at home for a total of 46 hours.  

Each cycle looks like this:

Day 1
Treatment Day:
Go to the hospital for FOLFIRINOX treatment. Fluorouracil infusion will continue for 46 hours.
2
Fluorouracil infusion continues at home.
3
Fluorouracil infusion continues at home.
A nurse will disconnect it.
4
No FOLFIRINOX Treatment
5
No FOLFIRINOX Treatment
6
No FOLFIRINOX Treatment
7
No FOLFIRINOX Treatment
8
No FOLFIRINOX Treatment
9
No FOLFIRINOX Treatment
10
No FOLFIRINOX Treatment
11
No FOLFIRINOX Treatment
12
No FOLFIRINOX Treatment
13
No FOLFIRINOX Treatment
14
No FOLFIRINOX Treatment

The dosage and schedule of FOLFIRINOX may vary depending on the individual patient’s condition and response to treatment. The healthcare team will monitor the patient closely during treatment to evaluate the effectiveness of the chemotherapy and manage any side effects that may occur.

It’s important for patients to follow the instructions of their healthcare team carefully and take all medications as directed to ensure the best possible outcome from FOLFIRINOX treatment.

FOLIRINOX Explained
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